1,3-Diphenylguanidine
Title: 1,3-Diphenylguanidine
CAS Registry Number: 102-06-7
CAS Name: N,N¢-Diphenylguanidine
Additional Names: sym-diphenylguanidine
Trademarks: Melaniline; Vulkazit
Molecular Formula: C13H13N3
Molecular Weight: 211.26
Percent Composition: C 73.91%, H 6.20%, N 19.89%
Literature References: Prepn: Naunton, J. Soc. Chem. Ind. London 45, 376T (1926); Macholdt-Erdniss, Ber. 91, 1992 (1958); Ferris, Schutz, J. Org. Chem. 28, 71 (1963). Pharmacology: P. Valade et al., C.R. Seances Soc. Biol. Ses Fil. 143, 815 (1949).
Properties: Crystals from ether, mp 150°. Dec at about 170°. d 1.13. Sparingly sol in water; sol in alcohol, chloroform, hot benzene, hot toluene; readily sol in dil mineral acids. Aq soln is strongly alkaline. MLD s.c. in guinea pigs: 200 mg/kg; i.v. in dogs: 25 mg/kg (Valade).
Melting point: mp 150°
Density: d 1.13
Toxicity data: MLD s.c. in guinea pigs: 200 mg/kg; i.v. in dogs: 25 mg/kg (Valade)
 
Derivative Type: Phthalate
Trademarks: Guantal
Molecular Formula: C34H32N6O4
Molecular Weight: 588.66
Percent Composition: C 69.37%, H 5.48%, N 14.28%, O 10.87%
Properties: Obtained as the hemihydrate, blue-white to light gray powder. mp 178°. d425 1.20. Sol in alcohol. Practically insol in benzene, gasoline.
Melting point: mp 178°
Density: d425 1.20
 
Use: Recommended as a primary material for standardizing acids. Free base and phthalate as accelerators for vulcanization of rubber.

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