1-Chloro-2,4-dinitrobenzene
Title: 1-Chloro-2,4-dinitrobenzene
CAS Registry Number: 97-00-7
Additional Names: 2,4-Dinitro-1-chlorobenzene; 4-chloro-1,3-dinitrobenzene; 6-chloro-1,3-dinitrobenzene
Molecular Formula: C6H3ClN2O4
Molecular Weight: 202.55
Percent Composition: C 35.58%, H 1.49%, Cl 17.50%, N 13.83%, O 31.60%
Literature References: Obtained by nitrating o-nitrochlorobenzene: Borsche, Rantscheff, Ann. 379, 152 (1911); Hodgson, Dodgson, J. Chem. Soc. 1948, 1006. The mixture of 2,4- and 2,6-dinitrochlorobenzenes (of which the 2,4-compd is present in largest amount) can be separated with an alkaline ethanol-water soln: Molard, Vaganay, Mem. Poudres 39, 111 (1957). Toxicity study: H. F. Smyth et al., Am. Ind. Hyg. Assoc. J. 23, 95 (1962).
Properties: Yellow crystals. Skin irritant. d ~1.7. mp 52-54°. bp 315°. Practically insol in water. Sparingly sol in cold, freely sol in hot alc; sol in ether, benzene, CS2. LD50 orally in rats: 1.07 g/kg (Smyth).
Melting point: mp 52-54°
Boiling point: bp 315°
Density: d ~1.7
Toxicity data: LD50 orally in rats: 1.07 g/kg (Smyth)
CAUTION: May cause dermatitis of both primary and allergic types.
Use: As a reagent for the detection and determination of nicotinic acid, nicotinamide, and other pyridine compds.

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