1-Naphthylisothiocyanate
Title: 1-Naphthylisothiocyanate
CAS Registry Number: 551-06-4
CAS Name: 1-Isothiocyanatonaphthalene
Additional Names: ANIT
Molecular Formula: C11H7NS
Molecular Weight: 185.24
Percent Composition: C 71.32%, H 3.81%, N 7.56%, S 17.31%
Line Formula: C10H7N=C=S
Literature References: Prepn: Cymerman-Craig et al., Org. Synth. coll. vol. IV, 700 (1963); Jochims, Ber. 101, 1746 (1968). Has been used with pyrethrum as insecticide. Toxicity studies: Schwartz, Warren, Public Health Rep. 54, 1426 (1939); Ambrose, Miller, Fed. Proc. 2, 74 (1943); Becker, Plaa, Toxicol. Appl. Pharmacol. 7, 804 (1965); Capizzo, Roberts, ibid. 17, 262 (1970).
Properties: White needles; practically odorless and tasteless, mp 58°. Insol in water. Freely sol in ether, benzene, hot alcohol, acetone, carbon tetrachloride, olive oil, petr ether. LD50 orally in mice: 245 mg/kg (Becker, Plaa).
Melting point: mp 58°
Toxicity data: LD50 orally in mice: 245 mg/kg (Becker, Plaa)
CAUTION: Hepatotoxic; may cause dermatitis.

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