17-Hydroxy-16-methylene-Delta6-progesterone
Title: 17-Hydroxy-16-methylene-D6-progesterone
CAS Registry Number: 10087-54-4
CAS Name: 17-Hydroxy-16-methylenepregna-4,6-diene-3,20-dione
Additional Names: 6-dehydro-17a-hydroxy-16-methyleneprogesterone
Molecular Formula: C22H28O3
Molecular Weight: 340.46
Percent Composition: C 77.61%, H 8.29%, O 14.10%
Literature References: Prepn: Syhora, Mazac, Collect. Czech. Chem. Commun. 29, 2351 (1964). Prepn of the 17-acetate: GB 901293 (1962 to Upjohn); Syhora, Mazac, loc. cit.; GB 963427 (1964 to E. Merck).
Properties: Crystals from methanol, mp 196.5-197°. [a]D20 -72.5°. uv max: 283 nm (log e 4.51).
Melting point: mp 196.5-197°
Optical Rotation: [a]D20 -72.5°
Absorption maximum: uv max: 283 nm (log e 4.51)
 
Derivative Type: 17-Acetate
CAS Registry Number: 805-84-5
Additional Names: 17-Acetoxy-16-methylenepregna-4,6-diene-3,20-dione; 17a-acetoxy-6-dehydro-16-methyleneprogesterone
Trademarks: Superlutin
Molecular Formula: C24H30O4
Molecular Weight: 382.49
Percent Composition: C 75.36%, H 7.91%, O 16.73%
Properties: Crystals from ethyl acetate, mp 233-234°. [a]D20 -132°. uv max: 283 nm (log e 4.50).
Melting point: mp 233-234°
Optical Rotation: [a]D20 -132°
Absorption maximum: uv max: 283 nm (log e 4.50)
 
Therap-Cat: Progestogen (oral).
Keywords: Progestogen.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

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