4-Hexylresorcinol
Title: 4-Hexylresorcinol
CAS Registry Number: 136-77-6
CAS Name: 4-Hexyl-1,3-benzenediol
Additional Names: 4-hexyl-1,3-dihydroxybenzene
Manufacturers' Codes: ST-37
Trademarks: Ascaryl (Wander); Caprokol (Merck & Co.); Crystoids (Merck & Co.); Gelovermin; Sucrets (SKB); Worm-Agen (Merz)
Molecular Formula: C12H18O2
Molecular Weight: 194.27
Percent Composition: C 74.19%, H 9.34%, O 16.47%
Literature References: Prepd by reduction of hexanoylresorcinol with zinc amalgam + dil HCl: Dohme et al., J. Am. Chem. Soc. 48, 1688 (1926); Twiss, ibid. 2206; DE 488419 and DE 489117 (both 1929 to Sharp & Dohme). Toxicity: Lamson et al., J. Pharmacol. Exp. Ther. 53, 198 (1935).
Properties: Pale yellow, heavy liq becoming solid on standing at room temp. Needles from benzene or petr ether, mp 67.5-69°. bp6-7 178-180°; bp13-14 198-200°; bp760 333-335°. Pungent odor; sharp astringent taste. Sol in ether, chloroform, acetone, alcohol, vegetable oils; slightly sol in petr ether; sol in about 2000 parts water. LD50 orally in rats: 550 mg/kg (Lamson).
Melting point: mp 67.5-69°
Boiling point: bp6-7 178-180°; bp13-14 198-200°; bp760 333-335°
Toxicity data: LD50 orally in rats: 550 mg/kg (Lamson)
CAUTION: Concd solns can cause irritation of skin, mucous membranes: Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) Section II, p 190.
Therap-Cat: Anthelmintic (Nematodes). Antiseptic (topical).
Therap-Cat-Vet: Anthelmintic.
Keywords: Anthelmintic (Nematodes).

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