4-Pregnene-11beta,17alpha,20beta,21-tetrol-3-one
Title: 4-Pregnene-11b,17a,20b,21-tetrol-3-one
CAS Registry Number: 116-58-5
CAS Name: 11b,17,20b,21-Tetrahydroxypregn-4-en-3-one
Additional Names: 17-(1,2-dihydroxyethyl)androsten-3-one-11,17-diol; Reichstein's substance E
Molecular Formula: C21H32O5
Molecular Weight: 364.48
Percent Composition: C 69.20%, H 8.85%, O 21.95%
Literature References: Occurs in adrenal cortex. Isoln: Reichstein, Helv. Chim. Acta 19, 29 (1936); 20, 953 (1937); Reichstein, von Euw, ibid. 24, 247E (1941).
Properties: Hydrated crystals from dil acetone, dec 125°. [a]D20 +87° (alc). [M]D +317°. uv max: 240 nm.
Optical Rotation: [a]D20 +87° (alc)
Absorption maximum: uv max: 240 nm
 
Derivative Type: 20,21-Diacetate
Properties: Crystals, dec 229-230°. [a]D20 +162.7°. [M]D +730° (acetone).
Optical Rotation: [a]D20 +162.7°. [M]D +730° (acetone)

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