Title: Calusterone
CAS Registry Number: 17021-26-0
CAS Name: (7b,17b)-17-Hydroxy-7,17-dimethylandrost-4-en-3-one
Additional Names: 7b,17a-dimethyltestosterone; methosarb
Manufacturers' Codes: U-22550
Molecular Formula: C21H32O2
Molecular Weight: 316.48
Percent Composition: C 79.70%, H 10.19%, O 10.11%
Literature References: Synthetic androgen epimeric with bolasterone, q.v. Has been used in treatment of breast cancer. Prepn: Campbell, Babcock, US 3029263; US 3341557 (1962, 1967 both to Upjohn). Clinical studies: Gordan et al., J. Am. Med. Assoc. 219, 483 (1972).
Properties: Crystals from acetone, mp 127-129°. [a]D +57° (CHCl3). uv max (alcohol): 243 nm.
Melting point: mp 127-129°
Optical Rotation: [a]D +57° (CHCl3)
Absorption maximum: uv max (alcohol): 243 nm
NOTE: This is a controlled substance (anabolic steroid): 21 CFR, 1308.13, as defined in 1300.01.

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