Title: Cyclomethycaine
CAS Registry Number: 139-62-8
CAS Name: 4-(Cyclohexyloxy)benzoic acid 3-(2-methyl-1-piperidinyl)propyl ester
Additional Names: p-cyclohexyloxybenzoic acid ester of N-(3-hydroxypropyl)pipecoline; 3-(2-methylpiperidino)propyl p-cyclohexyloxybenzoate
Trademarks: Surfacaine (Lilly); Surfathesin; Topocaine (Lilly)
Molecular Formula: C22H33NO3
Molecular Weight: 359.50
Percent Composition: C 73.50%, H 9.25%, N 3.90%, O 13.35%
Literature References: Prepn: McElvain, Carney, J. Am. Chem. Soc. 68, 2592 (1946), eidem, US 2439818 (1948). Toxicity data: Schmidt et al., Toxicol. Appl. Pharmacol. 1, 454 (1959).
Derivative Type: Hydrochloride
CAS Registry Number: 537-61-1
Molecular Formula: C22H33NO3.HCl
Molecular Weight: 395.96
Percent Composition: C 66.73%, H 8.65%, N 3.54%, O 12.12%, Cl 8.95%
Properties: Crystals, dec 178-180°. Soly in water: slightly >1 g/100 ml.
Derivative Type: Sulfate
Molecular Formula: (C22H33NO3)2.H2SO4
Molecular Weight: 817.08
Percent Composition: C 64.68%, H 8.39%, N 3.43%, O 19.58%, S 3.92%
Properties: Crystals, mod sol in water.
Therap-Cat: Topical anesthetic.
Therap-Cat-Vet: Surface anesthetic.
Keywords: Anesthetic (Local).

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