Difenpiramide
Title: Difenpiramide
CAS Registry Number: 51484-40-3
CAS Name: N-2-Pyridinyl-[1,1¢-biphenyl]-4-acetamide
Additional Names: diphenpyramide
Manufacturers' Codes: Z-876
Trademarks: Difenax (Zambeletti)
Molecular Formula: C19H16N2O
Molecular Weight: 288.34
Percent Composition: C 79.14%, H 5.59%, N 9.72%, O 5.55%
Literature References: Prepn: F. Tenconi, R. M. Tagliabue, DE 2325309 (1973 to Zambeletti); L. Molteni et al., US 3868380 (1975). Pharmacological properties: S. Caliari et al., Arzneim.-Forsch. 27, 2086 (1977). Physicochemical profile: A. Trebbi, G. Filippi, Boll. Chim. Farm. 118, 729 (1979). Therapeutic use: C. Ortolani et al., Clin. Ter. 89, 391 (1979).
Properties: Crystals, mp 122-124°. LD50 in male mice, rats (mg/kg): 2590, 2075 orally; 1421, 1396 i.p. (Caliari).
Melting point: mp 122-124°
Toxicity data: LD50 in male mice, rats (mg/kg): 2590, 2075 orally; 1421, 1396 i.p. (Caliari)
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal).

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