Title: Dioxethedrine
CAS Registry Number: 497-75-6
CAS Name: 4-[2-(Ethylamino)-1-hydroxypropyl]-1,2-benzenediol
Additional Names: N-ethyl-3,4-dihydroxynorephedrine; a-(1-ethylaminoethyl)protocatechuyl alcohol; 2-ethylamino-1-(3¢,4¢-dihydroxyphenyl)-1-propanol; 1-(3¢,4¢-dihydroxyphenyl)-2-ethylamino-1-propanol
Manufacturers' Codes: C-247
Molecular Formula: C11H17NO3
Molecular Weight: 211.26
Percent Composition: C 62.54%, H 8.11%, N 6.63%, O 22.72%
Literature References: b-Adrenergic agonist. Prepd by catalytic hydrogenation of the corresponding aminoketone: Lespagnol, Cuingnet, Ann. Pharm. Fr. 18, 445 (1960). Only one of the two possible isomers, believed to be the "erythro" form, was isolated.
Derivative Type: Hydrochloride
Molecular Formula: C11H17NO3.HCl
Molecular Weight: 247.72
Percent Composition: C 53.33%, H 7.32%, N 5.65%, O 19.38%, Cl 14.31%
Properties: Crystals from methanol + ether, mp 212-214°.
Melting point: mp 212-214°
NOTE: One of the ingredients of Bexol.
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.

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