Ecgonidine
Title: Ecgonidine
CAS Registry Number: 484-93-5
CAS Name: (1R)-8-Methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylic acid
Additional Names: 2-tropidinecarboxylic acid; anhydroecgonin
Molecular Formula: C9H13NO2
Molecular Weight: 167.21
Percent Composition: C 64.65%, H 7.84%, N 8.38%, O 19.14%
Literature References: Prepn from ecgonine and structure: Findlay, J. Am. Chem. Soc. 75, 1033 (1953). Prepn and formation of l-form: de Jong, Rec. Trav. Chim. 42, 980 (1923), 66, 99 (1947). Synthesis of dl-form: Grundmann, Ottmann, Ann. 605, 24 (1957); US 2783235 (1957 to Olin Mathieson).
 
Derivative Type: dl-Form
Properties: Crystals from alcohol + ether, dec 235-236°. Soluble in water; sparingly sol in alcohol.
 
Derivative Type: l-Form
Properties: Crystals from abs alcohol, mp 235°. [a]D14 -84.6° (c = 1.7).
Melting point: mp 235°
Optical Rotation: [a]D14 -84.6° (c = 1.7)
 
Therap-Cat: Anesthetic (topical).
Keywords: Anesthetic (Local).

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