Iopentol
Title: Iopentol
CAS Registry Number: 89797-00-2
CAS Name: 5-[Acetyl(2-hydroxy-3-methoxypropyl)amino]-N,N¢-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
Additional Names: N,N¢-bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxy-3-methoxypropyl)acetamido]-2,4,6-triiodoisophthalamide
Trademarks: Imagopaque (GE Healthcare)
Molecular Formula: C20H28I3N3O9
Molecular Weight: 835.16
Percent Composition: C 28.76%, H 3.38%, I 45.59%, N 5.03%, O 17.24%
Literature References: Nonionic, water soluble vascular contrast medium. Prepn: K. Wille, EP 105752 (1984 to Nyegaard A/S), C.A. 101, 72456e (1984). Synthesis and preparative LC purification: W. Skjold, A. Berg, J. Chromatogr. 366, 299 (1986). Effects on blood-brain barrier in animals: A. A. Michelet, Acta Radiol. 28, 329 (1987). Series of articles on clinical experience: Eur. Radiol. 7, Suppl. 4, S104-S161 (1997).
Properties: Osmolality (300 mg I/ml): 0.64 mol/kg H2O. Viscosity at 20° (300 mg I/ml): 13.2 mPa. Partition coefficient (1-octanol/water): 0.007.
Log P: Partition coefficient (1-octanol/water): 0.007
Therap-Cat: Diagnostic aid (radiopaque medium).
Keywords: Diagnostic Aid (Radiopaque Medium).

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