Title: Nitrofen
CAS Registry Number: 1836-75-5
CAS Name: 2,4-Dichloro-1-(4-nitrophenoxy)benzene
Additional Names: 2,4-dichlorophenyl-p-nitrophenyl ether; nitraphen; nitrophen; nitrofene
Manufacturers' Codes: FW-925
Trademarks: TOK (Rohm & Haas)
Molecular Formula: C12H7Cl2NO3
Molecular Weight: 284.09
Percent Composition: C 50.73%, H 2.48%, Cl 24.96%, N 4.93%, O 16.90%
Literature References: Selective pre- and post-emergence herbicide. Prepn: H. F. Wilson, H. M. Dougal, US 3080225 (1963 to Rohm & Haas). Toxicity studies: A. M. Ambrose et al., Toxicol. Appl. Pharmacol. 19, 263 (1971). Carcinogenicity studies: J. F. Robens, Vet. Hum. Toxicol. 22, 328 (1980). Review of carcinogenic risk: IARC Monographs 30, 271-282 (1983).
Properties: Crystalline solid, mp 70-71°. Vapor pressure at 40°: 8 ´ 10-6 mm Hg. Soly in water at 22°: 0.7-1.2 ppm. LD50 orally in rats: 3.58 g/kg (Ambrose).
Melting point: mp 70-71°
Toxicity data: LD50 orally in rats: 3.58 g/kg (Ambrose)
CAUTION: This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-192.
Use: Formerly as herbicide.

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