Norflurazon
Title: Norflurazon
CAS Registry Number: 27314-13-2
CAS Name: 4-Chloro-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]-3(2H)-pyridazinone
Additional Names: 4-chloro-5-(methylamino)-2-(a,a.a-trifluoro-m-tolyl)-3(2H)-pyridazinone; 1-(3-trifluoromethylphenyl)-4-methylamino-5-chloropyridazone
Manufacturers' Codes: SAN-9789
Trademarks: Solicam (Syngenta); Zorial (Syngenta)
Molecular Formula: C12H9ClF3N3O
Molecular Weight: 303.67
Percent Composition: C 47.46%, H 2.99%, Cl 11.67%, F 18.77%, N 13.84%, O 5.27%
Literature References: Selective pre-emergent herbicide which inhibits carotenoid biosynthesis in susceptible species. Prepn: C. Ebner, M. Schuler, BE 712832; eidem, US 3644355 (1968, 1972 both to Sandoz). Absorption and metabolism: R. H. Strang, R. L. Rogers, J. Agric. Food Chem. 22, 1119 (1974). Mechanism of action: G. Sandmann et al., Pestic. Biochem. Physiol. 14, 185 (1980). HPLC determn in edible crops: W. M. Draper, J. C. Street, J. Agric. Food Chem. 29, 724 (1981). Comprehensive description: E. Ummel et al., Proc. Brit. Weed Contr. Conf. 13, 313 (1976).
Properties: Crystals from alcohol, mp 183-185°. Soly in water (25°): 28 ppm. LD50 orally in rats: 9300 mg/kg (Ummel).
Melting point: mp 183-185°
Toxicity data: LD50 orally in rats: 9300 mg/kg (Ummel)
Use: Herbicide.

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