Phenacaine Hydrochloride
Title: Phenacaine Hydrochloride
CAS Registry Number: 620-99-5
CAS Name: N,N¢-Bis(4-ethoxyphenyl)ethanimidamide monohydrochloride
Additional Names: N1,N2-bis(p-ethoxyphenyl)acetamidine hydrochloride
Trademarks: Holocaine Hydrochloride (Winthrop)
Molecular Formula: C18H23ClN2O2
Molecular Weight: 334.84
Percent Composition: C 64.57%, H 6.92%, Cl 10.59%, N 8.37%, O 9.56%
Literature References: Prepn: DE 79868; DE 80568.
Derivative Type: Monohydrate
CAS Registry Number: 6153-19-1
Properties: Faintly bitter crystals producing transient numbness of the tongue. Stable in air. When anhydr, mp 190-192°. One gram dissolves in 50 ml water. Freely sol in boiling water, alcohol, chloroform. Insol in ether. Incompatible with alkalies and their carbonates and the usual alkaloidal reagents. Aq solns are stable and are not dec by boiling.
Melting point: mp 190-192°
Therap-Cat: Topical anesthetic (ophthalmic).
Therap-Cat-Vet: Ocular anesthetic.
Keywords: Anesthetic (Local).

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