Title: Phenesterine
CAS Registry Number: 3546-10-9
CAS Name: (3b)-Cholest-5-en-3-ol 4-[bis(2-chloroethyl)amino]benzeneacetate
Additional Names: p-[bis(2-chloroethyl)amino]phenylacetic acid cholesterol ester; cholesteryl p-bis(2-chloroethyl)aminophenylacetate; fenesterin
Molecular Formula: C39H59Cl2NO2
Molecular Weight: 644.80
Percent Composition: C 72.65%, H 9.22%, Cl 11.00%, N 2.17%, O 4.96%
Literature References: Prepd from p-bis(2-chloroethyl)aminophenylacetic acid chloride and cholesterol: Shkodinskaya et al., Zh. Obshch. Khim. 32, 959 (1962), C.A. 58, 2502h (1963).
Properties: Crystals, mp 90-90.5°. [a]D -13.7°.
Melting point: mp 90-90.5°
Optical Rotation: [a]D -13.7°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents; Nitrogen Mustards.
Status: This monograph has been retired and is no longer subject to revision or update. |