Title: Phenoperidine
CAS Registry Number: 562-26-5
CAS Name: 1-(3-Hydroxy-3-phenylpropyl)-4-phenyl-4-piperidinecarboxylic acid ethyl ester
Additional Names: 1-(3-hydroxy-3-phenylpropyl)-4-phenylisonipecotic acid ethyl ester; 1-[g-hydroxy-g-phenylpropyl]-4-phenyl-4-carbethoxypiperidine; 3-(4-carbethoxy-4-phenylpiperidino)-1-phenyl-1-propanol; 1-phenyl-3-[(4¢-phenyl-4¢-carbethoxy)piperidino]-1-propanol; phenoperidin
Molecular Formula: C23H29NO3
Molecular Weight: 367.48
Percent Composition: C 75.17%, H 7.95%, N 3.81%, O 13.06%
Literature References: Prepn: Janssen, Eddy, J. Med. Pharm. Chem. 2, 31 (1960); Pohland, US 2951080 (1960 to Lilly); Cutler, Fisher, US 2962501 (1960 to Merck & Co.).
Derivative Type: Hydrochloride
CAS Registry Number: 3627-49-4
Trademarks: Lealgin (Janssen); Operidine (Janssen)
Molecular Formula: C23H29NO3.HCl
Molecular Weight: 403.94
Percent Composition: C 68.39%, H 7.49%, N 3.47%, O 11.88%, Cl 8.78%
Properties: Crystals from ethyl acetate + methanol, or ethanol, mp 200-202°. Soluble in water.
Melting point: mp 200-202°
NOTE: This is a controlled substance (opiate): 21 CFR, 1308.11.
Therap-Cat: Analgesic (narcotic).
Keywords: Analgesic (Narcotic).

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