Phenyl Biguanide
Title: Phenyl Biguanide
CAS Registry Number: 102-02-3
CAS Name: N-Phenylimidodicarbonimidic diamide
Additional Names: phenyl diguanide; 1-phenylbiguanide; N-phenyl-N¢-guanylguanidine
Molecular Formula: C8H11N5
Molecular Weight: 177.21
Percent Composition: C 54.22%, H 6.26%, N 39.52%
Literature References: Prepd by reacting aniline hydrochloride and dicyandiamide in water: Cohn, J. Prakt. Chem. [2] 84, 396; from aniline, dicyandiamide in pyridine contg HCl: Jacobs, Jolles, GB 587907 (1947 to ICI).
Properties: Crystals from water or toluene. Sharp, somewhat bitter taste. mp 144-146°. pK1 10.76, pK2 2.13. Freely sol in water and in alcohol.
Melting point: mp 144-146°
pKa: pK1 10.76, pK2 2.13
Derivative Type: Hydrochloride
Molecular Formula: C8H11N5.HCl
Molecular Weight: 213.67
Percent Composition: C 44.97%, H 5.66%, N 32.78%, Cl 16.59%
Properties: Prisms, mp 237°. Sol in about 115 parts of water at 32°.
Melting point: mp 237°
Derivative Type: Nitrate
Molecular Formula: C8H11N5.HNO3
Molecular Weight: 240.22
Percent Composition: C 40.00%, H 5.04%, N 34.98%, O 19.98%
Properties: Crystals, mp 208-209°.
Melting point: mp 208-209°

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