Title: Pirozadil
CAS Registry Number: 54110-25-7
CAS Name: 3,4,5-Trimethoxybenzoic acid 2,6-pyridinediylbis(methylene)ester
Additional Names: 2,6-pyridinedimethanol bis(3,4,5-trimethoxybenzoate)
Manufacturers' Codes: 722 D
Trademarks: Pemix (Prodes)
Molecular Formula: C27H29NO10
Molecular Weight: 527.52
Percent Composition: C 61.47%, H 5.54%, N 2.66%, O 30.33%
Literature References: Hypolipidemic agent that inhibits platelet aggregation. Prepn: J. P. Cochs, DE 2411902 (1974 to Inst. Int. Ter.), C.A. 82, 4136q (1975). Effect on cerebral metabolic blood flow in rabbits: J. Balasch, L. Palacios, Arch. Farmacol. Toxicol. 3, 137 (1977). Efficacy in exptl atherosclerosis: M. R. Parwaresch et al., Atherosclerosis 31, 395 (1978). Toxicological and histopathological study: J. Roca et al., Arch. Farmacol. Toxicol. 6, 41 (1980). Clinical trials in hyperlipoproteinemia: M. Shinomiya et al., Arzneim.-Forsch. 37, 1069 (1987); R. Tapounet, I. Marti Ragué, Drugs Exp. Clin. Res. 13, 447 (1987).
Properties: White cryst powder, mp 119-126°. Very sol in chloroform; sol in dioxane, acetonitrile. Practically insol in ether, water.
Melting point: mp 119-126°
Therap-Cat: Antilipemic.
Keywords: Antilipemic.

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