Title:  Quinoxyfen 
CAS Registry Number:  124495-18-7 
CAS Name:  5,7-Dichloro-4-(4-fluorophenoxy)quinoline 
Manufacturers' Codes:  DE-795 
Trademarks:  Fortress (Dow AgroSci.);  Quintec (Dow AgroSci.) 
Molecular Formula:  C15H8Cl2FNO 
Molecular Weight:  308.13 
Percent Composition:  C 58.47%, H 2.62%, Cl 23.01%, F 6.17%, N 4.55%, O 5.19% 
Literature References:  Quinoline fungicide for powdery mildew control in cereals, grapes and hops; inhibits formation of appressoria through which the fungus invades the plant.  Prepn:  W. R. Arnold et al., EP 326330 (1989 to Eli Lilly); eidem, US 5145843 (1992 to DowElanco).  Properties and field trials:  C. Longhurst et al., Brighton Crop Prot. Conf. - Pests Dis. 1996, 27.  Resistance profile:  D. W. Hollomon et al., ibid. 701.  Metabolism and environmental fate:  G. L. Reeves et al., ibid. 1169.  Determn and fate in grapes, raisins and wine:  P. Cabras et al., J. Agric. Food Chem. 48, 6128 (2000). 
Properties:  Crystals from heptane, mp 105-106°.  LD50 orally in rats:  >5000 mg/kg; dermally in rabbits:  >2000 mg/kg; by inhalation in rats:  >3.38 mg/l (Longhurst). 
Melting point:  mp 105-106° 
Toxicity data:  LD50 orally in rats:  >5000 mg/kg; dermally in rabbits:  >2000 mg/kg; by inhalation in rats:  >3.38 mg/l (Longhurst) 
Use:  Agricultural fungicide.   |