Sodium Cyanate
Title: Sodium Cyanate
CAS Registry Number: 917-61-3
CAS Name: Cyanic acid sodium salt
Molecular Formula: CNNaO
Molecular Weight: 65.01
Percent Composition: C 18.48%, N 21.55%, Na 35.36%, O 24.61%
Line Formula: NaOCN
Literature References: Prepn and properties: Gmelins, Sodium (8th ed.) 21, 799-801 (1928) and supplement, part 4, 1382-1386 (1967). Used experimentally in treatment of sickle cell anemia. Effect of cyanate on sickling: May et al., Lancet 1, 658 (1972); P. N. Gillette et al., N. Engl. J. Med. 290, 654 (1974). Pharmacology and toxicology: Cerami et al. J. Pharmacol. Exp. Ther. 185, 653 (1973). Clinical studies: Peterson et al., ibid. 189, 577 (1974).
Properties: Colorless needles from alcohol. d420 1.893. mp 550°. Sol in water; decomposes to form Na2CO3 and urea. Soly in alc (0°): 0.22 g/100 g solvent. Insol in ether. LD50 i.p. in mice: 260 mg/kg (Cerami).
Melting point: mp 550°
Density: d420 1.893
Toxicity data: LD50 i.p. in mice: 260 mg/kg (Cerami)

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