Sodium Lauryl Sulfate
Title: Sodium Lauryl Sulfate
CAS Registry Number: 151-21-3
CAS Name: Sulfuric acid monododecyl ester sodium salt
Additional Names: sodium dodecyl sulfate; SDS
Trademarks: Irium
Molecular Formula: C12H25NaO4S
Molecular Weight: 288.38
Percent Composition: C 49.98%, H 8.74%, Na 7.97%, O 22.19%, S 11.12%
Line Formula: CH3(CH2)10CH2OSO3Na
Literature References: Anionic detergent prepd by sulfation of lauryl alcohol, followed by neutralization with sodium carbonate: A. Lottermoser, F. Stoll, Kolloid-Z. 63, 50 (1933). Surfactant properties: J. Powney, C. C. Addison, Trans. Faraday Soc. 33, 1244 (1937); E. E. Dreger et al., Ind. Eng. Chem. 36, 610 (1944). Use in electrophoretic sepn and mol wt estimation of proteins: A. L. Shapiro et al., Biochem. Biophys. Res. Commun. 28, 815 (1967); K. Weber, M. Osborn, J. Biol. Chem. 244, 4406 (1969); of glycopolypeptides: B. S. Leach et al., Biochemistry 19, 5734 (1980). Toxicity study: A. I. T. Walker et al., Food Cosmet. Toxicol. 5, 763 (1967). Review of toxicology: Ch. Gloxhuber, Arch. Toxicol. 32, 245-270 (1974).
Properties: White or cream-colored crystals, flakes, or powder. Faint odor of fatty substances. Smooth feel. Neutral reaction. One gram dissolves in 10 ml water, giving an opalescent soln. Lowers the surface tension of aq solns. Emulsifies fats. LD50 orally in rats: 1288 mg/kg (Walker).
Toxicity data: LD50 orally in rats: 1288 mg/kg (Walker)
Use: Wetting agent, detergent, esp in the textile industry. Electrophoretic separation of proteins and lipids. Ingredient of toothpastes.

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