Title: Thionazin
CAS Registry Number: 297-97-2
CAS Name: Phosphorothioic acid O,O-diethyl O-pyrazinyl ester
Additional Names: O,O-diethyl-O-(2-pyrazinyl) phosphorothioate; ethyl pyrazinyl phosphorothioate
Manufacturers' Codes: EN-18133; ENT-25580; American Cyanamid 18133
Trademarks: Cynem; Nemafos; Zinophos
Molecular Formula: C8H13N2O3PS
Molecular Weight: 248.24
Percent Composition: C 38.71%, H 5.28%, N 11.28%, O 19.34%, P 12.48%, S 12.92%
Literature References: Prepn: Dixon et al., US 2918468; Gordon, US 2938831; Miller, Forbes, US 3091614; Gagliardi, US 3340262 (1959, 1960, 1963, 1967 all to Am. Cyanamid). Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969).
Properties: Amber liquid, mp -1.7°. bp 80°. nD25 1.5131. Vapor pressure at 30°: 3 ´ 10-3 mm Hg. Slightly sol in water; misc with most organic solvents. LD50 in female, male rats (mg/kg): 3.5, 6.4 orally; 11, 17 dermally (Gaines).
Melting point: mp -1.7°
Boiling point: bp 80°
Index of refraction: nD25 1.5131
Toxicity data: LD50 in female, male rats (mg/kg): 3.5, 6.4 orally; 11, 17 dermally (Gaines)
CAUTION: Cholinesterase inhibitor. See Parathion.
Use: Nematocide; insecticide.
Status: This monograph has been retired and is no longer subject to revision or update.

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