Acranil?
Title: Acranil® (Bayer)
CAS Registry Number: 1684-42-0
CAS Name: 1-[(6-Chloro-2-methoxy-9-acridinyl)amino]-3-(diethylamino)-2-propanol dihydrochloride
Additional Names: 5-[(g-diethylamino-b-hydroxypropyl)amino]-3-methoxy-8-chloroacridine dihydrochloride
Manufacturers' Codes: SKF-16214-A2; SN-186
Molecular Formula: C21H28Cl3N3O2
Molecular Weight: 460.82
Percent Composition: C 54.73%, H 6.12%, Cl 23.08%, N 9.12%, O 6.94%
Literature References: Prepn: Mietzsch, Mauss, DE 553072 Frdl. 19, 1167; GB 363392; US 2113357 (1930, 1930, 1938 all to I. G. Farben.); Maghidson, Grigorovski, Ber. 69, 396 (1936); J. Gen. Chem. USSR 6, 806 (1936). Antiviral activity: T. E. Gláz et al., Antimicrob. Agents Chemother. 3, 537 (1973). Interferon induction and radioprotective activity: T. E. Glaz, M. Talas, Arch. Virol. 48, 375 (1975); M. Talas, E. Szolgay, ibid. 56, 309 (1978).
Properties: Bitter, yellow crystals, mp 237-239° (dec). Sol in water.
Melting point: mp 237-239° (dec)
 
Derivative Type: Free base
Molecular Formula: C21H26ClN3O2
Molecular Weight: 387.90
Percent Composition: C 65.02%, H 6.76%, Cl 9.14%, N 10.83%, O 8.25%
Properties: Yellow crystals, mp 105-107°. Sparingly sol in ether.
Melting point: mp 105-107°
 
Therap-Cat: Antiprotozoal (Giardia).
Keywords: Antiprotozoal (Giardia).

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