Alcuronium
Title: Alcuronium
CAS Registry Number: 23214-96-2
CAS Name: 4,4¢-Didemethyl-4,4¢-di-2-propenyltoxiferine I
Additional Names: N,N¢-diallylnortoxiferinium; diallylbis(nortoxiferine); diallylnortoxiferine; diallyltoxiferine
Molecular Formula: [C44H50N4O2]2+
Literature References: Prepn of dichloride and diiodide: Boller et al., US 3080373 (1963 to Hoffmann-La Roche).
 
Derivative Type: Dichloride
CAS Registry Number: 15180-03-7
Additional Names: N,N¢-Diallylnortoxiferinium dichloride
Manufacturers' Codes: Ro-4-3816
Trademarks: Alloferin (Roche)
Molecular Formula: C44H50Cl2N4O2
Molecular Weight: 737.80
Percent Composition: C 71.63%, H 6.83%, Cl 9.61%, N 7.59%, O 4.34%
Properties: Crystals from methanol or ethanol. Compd contains 5 moles of water of crystn after equilibration in air; [a]D22 -348° (methanol); uv max (methanol): 292 nm (e 43000).
Optical Rotation: [a]D22 -348° (methanol)
Absorption maximum: uv max (methanol): 292 nm (e 43000)
 
Derivative Type: Diiodide
Molecular Formula: C44H50I2N4O2
Molecular Weight: 920.70
Percent Composition: C 57.40%, H 5.47%, I 27.57%, N 6.09%, O 3.48%
Properties: Solid. uv max (methanol): 291 nm (e 39900).
Absorption maximum: uv max (methanol): 291 nm (e 39900)
 
Therap-Cat: Neuromuscular blocking agent.
Therap-Cat-Vet: Neuromuscular blocking agent.
Keywords: Neuromuscular Blocking Agent; Nondepolarizing Agents.

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