Alexidine
Title: Alexidine
CAS Registry Number: 22573-93-9
CAS Name: N,N¢¢-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
Additional Names: 1,1¢-hexamethylenebis[5-(2-ethylhexyl)biguanide]
Manufacturers' Codes: Win-21904; Sterwin 904
Trademarks: Bisguadine (Sterwin)
Molecular Formula: C26H56N10
Molecular Weight: 508.79
Percent Composition: C 61.38%, H 11.09%, N 27.53%
Literature References: Prepn from 1,1¢-hexamethylenebis(3-cyanoguanide) and 2-ethylhexylamine hydrochloride: FR 1463818 (1965 to Sterling Drug). Evaluation as antimicrobial agent: McNamara et al., J. Soc. Cosmet. Chem. 16, 499 (1965).
 
Derivative Type: Dihydrochloride
Properties: Crystals from methanol + ether, mp 220.6-223.4°.
Melting point: mp 220.6-223.4°
 
Therap-Cat: Antibacterial.
Keywords: Antiseptic/Disinfectant; Guanidines.

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