Alverine
Title: Alverine
CAS Registry Number: 150-59-4
CAS Name: N-Ethyl-N-(3-phenylpropyl)benzenepropanamine
Additional Names: N-ethyl-3,3¢-diphenyldipropylamine; bis(g-phenylpropyl)ethylamine; di(phenylpropyl)ethylamine
Molecular Formula: C20H27N
Molecular Weight: 281.44
Percent Composition: C 85.35%, H 9.67%, N 4.98%
Literature References: Prepn: Külz et al., Ber. 72, 2165 (1939); Stühner, Elbrächter, Arch. Pharm. 287, 139 (1954). Physical properties: E. F. Salim, W. R. Ebert, J. Pharm. Sci. 56, 1162 (1967). Clinical trial in irritable bowel syndrome: G. J. Tudor, Br. J. Clin. Pract. 40, 276 (1985).
Properties: Liquid, bp0.3 165-168°; bp13 210-215°.
Boiling point: bp0.3 165-168°; bp13 210-215°
 
Derivative Type: Citrate
CAS Registry Number: 5560-59-8
Trademarks: Spasmaverine (Bellon); Spasmonal (Norgine)
Molecular Formula: C20H27N.C6H8O7
Molecular Weight: 473.56
Percent Composition: C 65.94%, H 7.45%, N 2.96%, O 23.65%
Properties: White to off-white powder having a sweet odor and slightly bitter taste, mp 100-102°. Slightly sol in water, chloroform; sparingly sol in alcohol; very slightly sol in ether.
Melting point: mp 100-102°
 
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.

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