Azidamfenicol
Title: Azidamfenicol
CAS Registry Number: 13838-08-9
CAS Name: 2-Azido-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
Additional Names: D-(-)-threo-1-p-nitrophenyl-2-azidoacetylaminopropane-1,3-diol; D-(-)-threo-2-azidoacetamido-1-p-nitrophenyl-1,3-propanediol; azidoamphenicol
Trademarks: Berlicetin (Chauvin ankerpharm); Leukomycin-N (Bayer); Posifenicol (Ursapharm); Thilocanfol (Alcon)
Molecular Formula: C11H13N5O5
Molecular Weight: 295.25
Percent Composition: C 44.75%, H 4.44%, N 23.72%, O 27.09%
Literature References: Semi-synthetic antibiotic related to chloramphenicol, q.v. Prepn: Meiser, Domagk, US 2882275 (1959 to Bayer).
Properties: Crystals from ethylene chloride, mp 107°. [a]D20 -20° (c = 1.6 in ethyl acetate). pH 7.1. Sol in water up to 2%.
Melting point: mp 107°
Optical Rotation: [a]D20 -20° (c = 1.6 in ethyl acetate)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); Amphenicols.

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