Benziodarone
Title: Benziodarone
CAS Registry Number: 68-90-6
CAS Name: (2-Ethyl-3-benzofuranyl) (4-hydroxy-3,5-diiodophenyl) methanone
Additional Names: 2-ethyl-3-(3¢,5¢-diiodo-4¢-hydroxybenzoyl)benzofuran; 2-ethyl-3-(3¢,5¢-diiodo-4¢-hydroxybenzoyl)oxaindene; 2-ethyl-3-benzofuryl 3¢,5¢-diiodo-4¢-hydroxyphenyl ketone; 2-ethyl-3-(3,5-diiodo-4-hydroxybenzoyl)coumarone; 2-ethyl-3-(4-hydroxy-3,5-diiodobenzoyl)benzofuran
Manufacturers' Codes: 2329 Labaz; L-2329
Trademarks: Amplivix; Dilafurane
Molecular Formula: C17H12I2O3
Molecular Weight: 518.08
Percent Composition: C 39.41%, H 2.33%, I 48.99%, O 9.26%
Literature References: Description: Charlier, Acta Cardiol. Suppl. 7, 1-60 (1959). Synthesis: Beaudet, Henaux, BE 553621; GB 836272 (1957, 1960, both to Labaz); Buu-Hoi, Beaudet, US 3012042 (1961 to Soc. Belge Azote Prod. Chim. Marly). Clinical trial in hyperuricemia in renal transplant patients: F. Perez-Ruiz et al., Nephrol. Dial. Transplant. 18, 603 (2003).
Properties: Yellowish powder, mp 167°. Soly in water at 25° about 0.2%, at 45° about 1.0%. Sol in chloroform, acetone.
Melting point: mp 167°
Therap-Cat: Uricosuric.
Keywords: Uricosuric.

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