Benzoctamine
Title: Benzoctamine
CAS Registry Number: 17243-39-9
CAS Name: N-Methyl-9,10-ethanoanthracene-9(10H)-methanamine
Additional Names: 1-(methylaminomethyl)dibenzo[b,e]bicyclo[2.2.2]octadiene; 9-(methylaminomethyl)-9,10-dihydro-9,10-ethanoanthracene
Molecular Formula: C18H19N
Molecular Weight: 249.35
Percent Composition: C 86.70%, H 7.68%, N 5.62%
Literature References: Prepn: BE 610863; P. Schmidt et al., US 3399201 (1962, 1968 to Ciba); Wilhelm, Schmidt, Helv. Chim. Acta 52, 1385 (1969). Pharmacology: Keberle et al., Present Status Psychotropic Drugs (Excerpta Medica, New York, 1969) p 123; Baltzer, Bein, Arch. Int. Pharmacodyn. Ther. 201, 25 (1973). Toxicity: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
 
Derivative Type: Hydrochloride
CAS Registry Number: 10085-81-1
Manufacturers' Codes: Ba-30803
Trademarks: Tacitin (Novartis)
Molecular Formula: C18H19N.HCl
Molecular Weight: 285.81
Percent Composition: C 75.64%, H 7.05%, N 4.90%, Cl 12.40%
Properties: Crystals, mp 320-322°. pKa: 7.6. LD50 orally in rats: 700 ±170 mg/kg (Goldenthal).
Melting point: mp 320-322°
pKa: pKa: 7.6
Toxicity data: LD50 orally in rats: 700 ±170 mg/kg (Goldenthal)
 
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic.

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