Bitoscanate
Title: Bitoscanate
CAS Registry Number: 4044-65-9
CAS Name: 1,4-Diisothiocyanatobenzene
Additional Names: phenylene-1,4-diisothiocyanate; isothiocyanic acid p-phenylene ester
Trademarks: Jonit (Hoechst)
Molecular Formula: C8H4N2S2
Molecular Weight: 192.26
Percent Composition: C 49.98%, H 2.10%, N 14.57%, S 33.36%
Literature References: Prepn: Lieber, Slutkin, J. Org. Chem. 27, 2214 (1962). Prepn and use as anthelmintic: FR M1652 and GB 1001314 (1963, 1965 to Hoechst). Purification: Soeder, Laemmer, DE 1172664 (1964 to Hoechst). Series of articles on clinical studies: Progress in Drug Research vol. 19, E. Jucker, Ed. (Birkhäuser Verlag, Basel and Stuttgart, 1975) pp 2-107.
Properties: Tasteless, odorless, colorless needles, from acetic acid or acetone, mp 132°.
Melting point: mp 132°
Therap-Cat: Anthelmintic (Nematodes).
Keywords: Anthelmintic (Nematodes).

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