Title: Butethal
CAS Registry Number: 77-28-1
CAS Name: 5-Butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
Additional Names: 5-butyl-5-ethylbarbituric acid; butobarbitone
Trademarks: Soneryl (M & B); Neonal (Abbott); Butobarbital; Etoval
Molecular Formula: C10H16N2O3
Molecular Weight: 212.25
Percent Composition: C 56.59%, H 7.60%, N 13.20%, O 22.61%
Literature References: Prepn: US 1609520 (1926). Pharmacology and toxicity: G. A. Alles et al., J. Pharmacol. Exp. Ther. 89, 356 (1947).
Properties: Crystals. Slightly bitter taste. mp 124-127°. One gram dissolves in about 5 ml alcohol, 10 ml ether. Practically insol in water; insol in petr ether, aliphatic hydrocarbons. LD50 i.p. in mice: 1.506 mM/kg (Alles).
Melting point: mp 124-127°
Toxicity data: LD50 i.p. in mice: 1.506 mM/kg (Alles)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.

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