Carmoxirole
Title: Carmoxirole
CAS Registry Number: 98323-83-2
CAS Name: 3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid
Molecular Formula: C24H26N2O2
Molecular Weight: 374.48
Percent Composition: C 76.98%, H 7.00%, N 7.48%, O 8.54%
Literature References: Selective, presynaptic dopamine D2-receptor agonist. Prepn: H. Böttcher et al., DE 3342632; eidem, US 5256673 (1985, 1993 both to E. Merck); H. Böttcher, R. Gericke, Ann. 1988, 749. Neurochemical profile: A. F. Haase et al., Arch. Pharmacol. 343, 588 (1991). Pharmacology: G. Haeusler et al., Eur. Heart J. 13, Suppl. D, 129 (1992). Pharmacokinetics and clinical evaluation: W. Meyer et al., ibid. 121.
Properties: Crystals, mp 284-285°.
Melting point: mp 284-285°
 
Derivative Type: Hydrochloride
CAS Registry Number: 115092-85-8
Manufacturers' Codes: EMD-45609
Molecular Formula: C24H25N2O2.HCl
Molecular Weight: 409.93
Percent Composition: C 70.32%, H 6.39%, N 6.83%, O 7.81%, Cl 8.65%
Properties: Crystals obtained as 0.25 H2O, mp 298-299°. uv max (methanol): 242, 281 nm.
Melting point: mp 298-299°
Absorption maximum: uv max (methanol): 242, 281 nm
 
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Dopamine Receptor Agonist.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.

Others monographs:
DOMNorflurazonLithium AcetateMeerwein's Reagent
SizofiranAlagebrium ChlorideMichler's BaseBevonium Methyl Sulfate
AntivirinPetroleumFerric Sodium PyrophosphateCelestin Blue
FagarineLigninRayonFluorescamine
©2016 DrugLead US FDA&EMEA