Ceftiofur
Title: Ceftiofur
CAS Registry Number: 80370-57-6
CAS Name: (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Additional Names: (6R,7R)-7-[2-(2-amino-4-thiazolyl)glyoxylamido]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 72-(Z)-(O-methyloxime) 2-furoate (ester)
Trademarks: Excede (Pfizer)
Molecular Formula: C19H17N5O7S3
Molecular Weight: 523.56
Percent Composition: C 43.59%, H 3.27%, N 13.38%, O 21.39%, S 18.37%
Literature References: Broad spectrum, third generation cephalosporin antibiotic. Prepn: B. Labeeuw, A. Salhi, EP 36812; eidem, US 4464367 (1981, 1984 both to Sanofi). In vivo and in vitro antibacterial activity and b-lactamase stability: R. J. Yancey et al., Am. J. Vet. Res. 48, 1050 (1987).
 
Derivative Type: Monosodium salt
CAS Registry Number: 104010-37-9
Manufacturers' Codes: CM-31916; U-64279E
Trademarks: Naxcel (Pfizer)
Molecular Formula: C19H16N5NaO7S3
Molecular Weight: 545.54
Percent Composition: C 41.83%, H 2.96%, N 12.84%, Na 4.21%, O 20.53%, S 17.63%
 
Derivative Type: Monohydrochloride
CAS Registry Number: 103980-44-5
Manufacturers' Codes: U-67279A
Trademarks: Excenel (Pfizer)
Molecular Formula: C19H17N5O7S3.HCl
Molecular Weight: 560.02
Percent Composition: C 40.75%, H 3.24%, N 12.51%, O 20.00%, S 17.18%, Cl 6.33%
 
Therap-Cat-Vet: Antibacterial.

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