Chlorfenvinphos
Title: Chlorfenvinphos
CAS Registry Number: 470-90-6
CAS Name: Phosphoric acid 2-chloro-1-(2,4-dichlorophenyl)ethenyl diethyl ester
Additional Names: O,O-diethyl O-[2-chloro-1-(2,4-dichlorophenyl)vinyl] phosphate; 2,4-dichloro-a-(chloromethylene)benzyl alcohol diethyl phosphate; CVP
Manufacturers' Codes: SD-7859; Compd 4072
Trademarks: Birlane (BASF); Steladone (Syngenta); Supona (BASF)
Molecular Formula: C12H14Cl3O4P
Molecular Weight: 359.57
Percent Composition: C 40.08%, H 3.92%, Cl 29.58%, O 17.80%, P 8.61%
Literature References: Organophosphorous insecticide; acetylcholinesterase inhibitor. Commercial prepn contains at least 90% of the active Z-isomer. Prepn: E. E. Gilbert et al., US 3003916 (1961 to Allied Chemical); Phillips et al., US 3102842 (1963 to Shell); Whetstone, Phillips et al., J. Agric. Food Chem. 14, 352 (1966). Metabolism: W. F. Chamberlain, D. E. Hopkins, J. Econ. Entomol. 55, 86 (1962); D. H. Hotson et al., Biochem. J. 102, 133 (1967). Toxicity studies: A. M. Ambrose et al., Toxicol. Appl. Pharmacol. 17, 323 (1970); Bunyan et al., Pestic. Sci. 2, 148 (1971). Review of toxicology and human exposure: Toxicological Profile for Chlorfenvinphos (PB98-101116, 1997) 220 pp.
Properties: Amber liquid, mild odor, bp0.001 120°, bp0.5 167-170°. Vapor press at 25°C: 7.5 ´ 10-6 mm Hg. nD25 1.5272. Soly in water at 23°: 145 ppm. Miscible with acetone, ethanol, propylene glycol. Slowly hydrolyzed by water. Corrosive to metal. LD50 in rats (mg/kg): 6.6 i.v.; 9.66 orally (Ambrose).
Boiling point: bp0.001 120°; bp0.5 167-170°
Index of refraction: nD25 1.5272
Toxicity data: LD50 in rats (mg/kg): 6.6 i.v.; 9.66 orally (Ambrose)
CAUTION: Potential symptoms of overexposure are headache, dizziness, weakness, feeling of anxiety, confusion, runny nose, constriction of pupils, blurred vision, nausea, vomiting, abdominal cramps, slow pulse, diarrhea, difficulty breathing, fainting (PB98-101116).
Use: Insecticide; acaricide.

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