Chloroacetaldehyde
Title: Chloroacetaldehyde
CAS Registry Number: 107-20-0
Additional Names: 2-Chloro-1-ethanal; monochloroacetaldehyde
Molecular Formula: C2H3ClO
Molecular Weight: 78.50
Percent Composition: C 30.60%, H 3.85%, Cl 45.16%, O 20.38%
Line Formula: ClCH2CHO
Literature References: Prepd industrially by carefully controlled chlorination of acetaldehyde: Söll, DE 844595 (1943 to Knapsack-Griesheim); Shawinigan Chem. Ltd., GB 644914 (1947); Guinot, Tabuteau, Compt. Rend. 231, 234 (1950); FR 1012991 (1950 to Comp. des Prod. Chim. et Electrometallurg.).
Properties: Liquid. Acrid, penetrating odor. bp760 85-86°. The anhydr substance polymerizes on standing but reverts to the monomer on distillation.
Boiling point: bp760 85-86°
 
Derivative Type: Hemihydrate
Properties: Probably ClCH2CH(OH)OCH(OH)CH2Cl, platelets from water, mp 43-50°, bp 85.5° with decompn into water and chloraldehyde. Sol in water, alcohol, ether.
Melting point: mp 43-50°
Boiling point: bp 85.5° with decompn into water and chloraldehyde
 
CAUTION: Potential symptoms of overexposure are irritation of eyes, skin and mucous membranes; skin burns; eye damage; pulmonary edema; skin, respiratory system sensitization. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 60.
Use: In the manufacture of 2-aminothiazole; to facilitate bark removal from tree trunks.

Others monographs:
TesaglitazarPolyethyleneRapeseed OilCadherins
RapamycinSqualaneNutgallMethandriol
Diperodon HydrochlorideEthyl BromideTitanium HydrideMotretinide
AcetamidePellitorineBismuth IodideChloral Ammonia
©2016 DrugLead US FDA&EMEA