Cotinine
Title: Cotinine
CAS Registry Number: 486-56-6
CAS Name: 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
Additional Names: N-methyl-2-(3-pyridyl)-5-pyrrolidone
Molecular Formula: C10H12N2O
Molecular Weight: 176.22
Percent Composition: C 68.16%, H 6.86%, N 15.90%, O 9.08%
Literature References: Nicotine metabolite first described by Pinner, Arch. Pharm. 231, 378 (1893). Isolated from autoxidized nicotine, nicotine treated with hydrogen peroxide, from nicotine irradiated with ultraviolet light: Frankenburg, Vaitekunas, J. Am. Chem. Soc. 79, 149 (1957).
Properties: Viscous oil, bp6 210-211°. Absorption spectra: Frankenburg, Vaitekunas, loc. cit.
Boiling point: bp6 210-211°
 
Derivative Type: Fumarate
CAS Registry Number: 5695-98-7
Trademarks: Scotine (Unimed)
Molecular Formula: (C10H12N2O)2.C4H4O4
Molecular Weight: 468.50
Percent Composition: C 61.53%, H 6.02%, N 11.96%, O 20.49%
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Pyrrolidones.

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