Cyclodrine
Title: Cyclodrine
CAS Registry Number: 52109-93-0
CAS Name: 1-Hydroxy-a-phenylcyclopentaneacetic acid 2-diethylaminoethyl ester
Additional Names: b-diethylaminoethyl (1-hydroxycyclopentyl)phenylacetate; 2-phenyl-2-(1-hydroxycyclopentyl)acetic acid b-(diethylamino)ethyl ester
Molecular Formula: C19H29NO3
Molecular Weight: 319.44
Percent Composition: C 71.44%, H 9.15%, N 4.38%, O 15.03%
Literature References: Anticholinergic. Prepn: Blicke, US 2922795 (1960 to Univ. of Michigan). Activity studies: Lands, Luduena, J. Pharmacol. Exp. Ther. 117, 331 (1956); Karczman, Long, ibid. 123, 230 (1958).
 
Derivative Type: Hydrochloride
CAS Registry Number: 78853-39-1
Manufacturers' Codes: GT-92
Trademarks: Cyclopent (Jenapharm)
Molecular Formula: C19H29NO3.HCl
Molecular Weight: 355.90
Percent Composition: C 64.12%, H 8.50%, N 3.94%, O 13.49%, Cl 9.96%
Properties: Crystals from isopropanol-isopropyl ether, mp 133-135°.
Melting point: mp 133-135°
 
Therap-Cat: Mydriatic.
Keywords: Antimuscarinic; Mydriatic.

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