Cyclopropane
Title: Cyclopropane
CAS Registry Number: 75-19-4
Additional Names: Trimethylene
Molecular Formula: C3H6
Molecular Weight: 42.08
Percent Composition: C 85.63%, H 14.37%
Literature References: Prepd by reduction of 1,2-dibromocyclopropane with zinc and alcohol: Lott, Christiansen, J. Am. Pharm. Assoc. 19, 341 (1930); Schlatter, J. Am. Chem. Soc. 63, 1733 (1941); from 1,3-dibromopropane with zinc and alcohol in absence of water: Ashdown et al., ibid. 58, 850 (1936); by the action of sodium vapor on 1,3-dibromopropane: Bawn, Hunter, Trans. Faraday Soc. 34, 608 (1938); from 1,3-dichloropropane heated with an excess of zinc dust, iodine and ethanol in 80% yield: Hass et al., Ind. Eng. Chem. 28, 1178 (1936); from 1,3-dichloropropane with zinc in presence of sodium iodide: US 2102556 (1937); cf. US 2098239; GB 498225; US 2211787; US 2235679; US 2235762; US 2240513; US 2240514; US 2242235. From ethylene by the reaction with methylene iodide and a zinc-copper couple in 29% yield: Simmons, Smith, J. Am. Chem. Soc. 80, 5323 (1958); Chem. Eng. News 36, 40 (Dec 8, 1958).
Properties: Flammable gas. Characteristic odor resembling that of petr ether. mp -127°. bp -33°. Liquefies at 4-6 atms. One liter of cyclopropane (at 1 atm, 0°) weighs 1.879 g. One vol of cyclopropane dissolves in about 2.7 vols of water at 15°. Freely sol in alcohol, ether. Sol in fixed oils. Concd H2SO4 absorbs the gas readily.
Melting point: mp -127°
Boiling point: bp -33°
CAUTION: Mixture of cyclopropane with oxygen or air may explode when brought in contact with a flame or other causes of ignition. Explosive limits (% by vol in air), lower: 2.41; upper: 10.3. The explosibility is greater than that of other anesthetic-oxygen mixtures because of the comparatively larger amounts of oxygen that are compatible with cyclopropane anesthesia. Rich oxygen mixtures are therefore to be avoided.
Therap-Cat: Anesthetic (inhalation).
Therap-Cat-Vet: Anesthetic (inhalation).
Keywords: Anesthetic (Inhalation).

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