Desaspidin BB
Title: Desaspidin BB
CAS Registry Number: 114-43-2
CAS Name: 2-[[2,4-Dihydroxy-6-methoxy-3-(1-oxobutyl)phenyl]methyl]-3,5-dihydroxy-4,4-dimethyl-6-(1-oxobutyl)-2,5-cyclohexadien-1-one
Additional Names: 3¢-[(5-butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl]-2¢,6¢-dihydroxy-4¢-methoxybutyrophenone; desaspidin; rosapin
Molecular Formula: C24H30O8
Molecular Weight: 446.49
Percent Composition: C 64.56%, H 6.77%, O 28.67%
Literature References: Isoln from the rhizome of Dryopteris austriaca (Jacq.) Wojnar, Polypodiaceae: Aebi et al., Helv. Chim. Acta 40, 266 (1957); from D. caucasica (A. Br.) Fraser-Jenkins et Corley: Widén et al., ibid. 56, 831 (1973). Structure: Aebi et al., ibid. 40, 572 (1957). Toxicity study: Airaksinan et al., Acta Pharmacol. Toxicol. 25, 33 (1967).
Properties: Crystals from ether + petr ether, mp 150-150.5°. uv max: 230, 274 nm (e 23000, 16800) in cyclohexane. Freely sol in ether, benzene, acetone. Practically insol in methanol, ethanol, petr ether. LD50 orally in mice: 340 mg/kg (Airaksinan).
Melting point: mp 150-150.5°
Absorption maximum: uv max: 230, 274 nm (e 23000, 16800) in cyclohexane
Toxicity data: LD50 orally in mice: 340 mg/kg (Airaksinan)

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