Diclazuril
Title: Diclazuril
CAS Registry Number: 101831-37-2
CAS Name: 2,6-Dichloro-a-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)benzeneacetonitrile
Additional Names: (p-chlorophenyl)[2,6-dichloro-4-(4,5-dihydro-3,5-dioxo-as-triazin-2(3H)-yl)phenyl]acetonitrile
Manufacturers' Codes: R-64433
Trademarks: Clinacox (Janssen)
Molecular Formula: C17H9Cl3N4O2
Molecular Weight: 407.64
Percent Composition: C 50.09%, H 2.23%, Cl 26.09%, N 13.74%, O 7.85%
Literature References: Nucleotide analog with broad-spectrum anticoccidial activity. Prepn: G. M. Boeckx et al., EP 170316; eidem, US 4631278 (both 1986 to Janssen). Mechanism of action studies: L. Maes et al., J. Parasitol. 74, 931 (1988); A. Verheyen et al., ibid. 939. Efficacy against Eimeria species in turkeys: O. Vanparijs et al., Avian Dis. 33, 479 (1989); in chickens: O. Vanparijs et al., Poult. Sci. 69, 60 (1990). Preliminary evaluation in coccidial enteritis in AIDS patients: K. Kayembe et al., Lancet 1, 1397 (1989).
Properties: mp 290.5°.
Melting point: mp 290.5°
Therap-Cat-Vet: Coccidiostat.

Others monographs:
IodipamideOrnithinePotassium MetabisulfiteNatural Gas
DeferasiroxAmmonium Hypophosphite11-DehydrocorticosteroneMethysergide
p-DimethylaminobenzophenoneBenzenesulfonic AnhydrideFemoxetinePirenzepine
PentagestroneIsopropyl AlcoholCuprous Mercuric IodidePropacetamol
©2016 DrugLead US FDA&EMEA