Dimethoate
Title: Dimethoate
CAS Registry Number: 60-51-5
CAS Name: Phosphorodithioic acid O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] ester
Additional Names: phosphorodithioic acid O,O-dimethyl ester, ester with 2-mercapto-N-methylacetamide; O,O-dimethyl S-methylcarbamoylmethyl phosphorodithioate
Manufacturers' Codes: American Cyanamid 12880
Trademarks: Cygon; Fostion MM (Agrimont); Perfekthion (BASF); Rogor (Isagro); Roxion (BASF)
Molecular Formula: C5H12NO3PS2
Molecular Weight: 229.26
Percent Composition: C 26.19%, H 5.28%, N 6.11%, O 20.94%, P 13.51%, S 27.97%
Literature References: Prepn: Cassaday et al., Young, US 2494283 and US 2996531 (1950, 1961, both to Am. Cyanamid); GB 791824 (1958 to Montecatini), C.A. 52, 18222 (1958). Toxicity data: E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972). Teratogenicity study: K. D. Courtney et al., J. Environ. Sci. Health B20, 373 (1985).
Properties: Crystals, mp 52-52.5°. d65 1.277. nD65 1.5334. Burns readily on contact with flame. Very slightly sol in water. Freely sol in most organic solvents, except saturated hydrocarbons. Stable in aq soln; hydrolyzed by aq alkali. LD50 orally in rats: 250 mg/kg (Schafer).
Melting point: mp 52-52.5°
Index of refraction: nD65 1.5334
Density: d65 1.277
Toxicity data: LD50 orally in rats: 250 mg/kg (Schafer)
CAUTION: Cholinesterase inhibitor: Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) Section II, p 297.
Use: Systemic and contact insecticide.

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