Dioxathion
Title: Dioxathion
CAS Registry Number: 78-34-2
CAS Name: Phosphorodithioic acid S,S¢-1,4-dioxane-2,3-diyl O,O,O¢,O¢-tetraethyl ester
Additional Names: 2,3-p-dioxanedithiol S,S-bis(O,O-diethyl phosphorodithioate)
Manufacturers' Codes: AC-528; ENT-22879; Hercules 528
Trademarks: Delnav (Hercules); Navadel (Hercules)
Molecular Formula: C12H26O6P2S4
Molecular Weight: 456.54
Percent Composition: C 31.57%, H 5.74%, O 21.03%, P 13.57%, S 28.09%
Literature References: Prepn: Diveley, Lohr, US 2725328; Speck, US 2815350 (1955, 1957 both to Hercules); Diveley et al., J. Am. Chem. Soc. 81, 139 (1959). Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969).
Properties: Tan liquid, d426 1.257. mp -20°. nD20 1.5420. Practically insol in water. Partly sol in hexane. Hydrolyzed by alkali and by heating. LD50 in female, male rats (mg/kg): 23, 43 orally; 63, 235 dermally (Gaines).
Melting point: mp -20°
Index of refraction: nD20 1.5420
Density: d426 1.257
Toxicity data: LD50 in female, male rats (mg/kg): 23, 43 orally; 63, 235 dermally (Gaines)
CAUTION: Potential symptoms of overexposure are eye, skin irritation; headache, giddiness, vertigo, weakness; rhinorrhea, chest tightness; miosis; nausea, vomiting, abdominal cramps, diarrhea, salivation; muscle fasciculations; confusion, drowsiness. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 120.
Use: Insecticide; acaricide.

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