Eprozinol
Title: Eprozinol
CAS Registry Number: 32665-36-4
CAS Name: 4-(2-Methoxy-2-phenylethyl)-a-phenyl-1-piperazinepropanol
Additional Names: 1-(2-methoxy-2-phenylethyl)-4-(3-hydroxy-3-phenylpropyl)piperazine
Molecular Formula: C22H30N2O2
Molecular Weight: 354.49
Percent Composition: C 74.54%, H 8.53%, N 7.90%, O 9.03%
Literature References: Prepn: Saunders, GB 1188505 (1970); to R. Y. Mauvernay, N. Busch, US 3705244 (1972). Pharmacology: Duchene-Marullaz et al., Therapie 26, 155 (1971). Clinical studies: Sors, Dutarte, ibid. 163.
 
Derivative Type: Dihydrochloride
CAS Registry Number: 27588-43-8
Trademarks: Alecor (Andromaco); Brovel (Lepetit); Eupnéron (Lyocentre)
Molecular Formula: C22H30N2O2.2HCl
Molecular Weight: 427.41
Percent Composition: C 61.82%, H 7.55%, N 6.55%, O 7.49%, Cl 16.59%
Properties: White crystalline powder, mp 164°. Sol in water and alcohol. LD50 orally in mice: 500 mg/kg (Mauvernay, Busch).
Melting point: mp 164°
Toxicity data: LD50 orally in mice: 500 mg/kg (Mauvernay, Busch)
 
Therap-Cat: Bronchodilator.
Keywords: Bronchodilator; Ephedrine Derivatives.

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