Ethamsylate
Title: Ethamsylate
CAS Registry Number: 2624-44-4
CAS Name: 2,5-Dihydroxybenzenesulfonic acid compd with N-ethylethanamine
Additional Names: diethylammonium 2,5-dihydroxybenzenesulfonate; 1-hydroxy-4-oxo-2,5-cyclohexadiene-1-sulfonic acid compd with diethylamine; diethylammonium cyclohexadien-4-ol-1-one-4-sulfonate; cyclonamine; etamsylate
Manufacturers' Codes: MD-141; E-141
Trademarks: Aglumin; Altodor (Synthelabo); Biosinon (Farmakhim); Dicynene (Lorex); Dicynone (OM)
Molecular Formula: C10H17NO5S
Molecular Weight: 263.31
Percent Composition: C 45.61%, H 6.51%, N 5.32%, O 30.38%, S 12.18%
Literature References: Prepn: GB 895709 (1962 to Labs. OM); ES 279303 (1962 to Labs. Esteve), C.A. 60, 1652g (1964). Pharmacology: Demars, Med. Exp. 4, 173 (1961); Huguet et al., Therapie 24, 429 (1969). Toxicity: Esteve et al., Therapie 15, 110 (1960).
Properties: Crystals from ethanol, mp 125°. LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve).
Melting point: mp 125°
Toxicity data: LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)
Therap-Cat: Hemostatic.
Keywords: Hemostatic.

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