Ethenzamide
Title: Ethenzamide
CAS Registry Number: 938-73-8
CAS Name: 2-Ethoxybenzamide
Additional Names: ethbenzamide; 2-ethoxybenzenecarbonamide; salicylamide o-ethyl ether
Trademarks: Lucamide; Protopyrin; Trancalgyl
Molecular Formula: C9H11NO2
Molecular Weight: 165.19
Percent Composition: C 65.44%, H 6.71%, N 8.48%, O 19.37%
Literature References: Prepn: GB 656746 (1951 to H. Lundbeck); Shapiro et al., J. Am. Chem. Soc. 81, 3728 (1959); Bryk, Osowski, PL 47822 (1961 to Polfa), C.A. 61, 5573f (1964). Metabolism: Davison et al., J. Pharmacol. Exp. Ther. 136, 226 (1962). Toxicity data: Starmer et al., Toxicol. Appl. Pharmacol. 19, 20 (1971).
Properties: Crystals from ethyl acetate + hexane, mp 132-134°. LD50 orally in mice: 1160 mg/kg (Starmer).
Melting point: mp 132-134°
Toxicity data: LD50 orally in mice: 1160 mg/kg (Starmer)
Therap-Cat: Analgesic.
Keywords: Analgesic (Non-Narcotic).

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