Ethion
Title: Ethion
CAS Registry Number: 563-12-2
CAS Name: Phosphorodithioic acid S,S¢-methylene O,O,O¢,O¢-tetraethyl ester
Additional Names: ethyl methylene phosphorodithioate; O,O,O¢,O¢-tetraethyl S,S¢-methylenediphosphorodithioate; bis[S-(diethoxyphosphinothioyl)mercapto]methane; diethion
Manufacturers' Codes: ENT-24105; FMC-1240; Niagara 1240
Trademarks: Commando (Boehringer, Ing.); Rhodocide (Aventis); Tafethion (Rallis)
Molecular Formula: C9H22O4P2S4
Molecular Weight: 384.48
Percent Composition: C 28.11%, H 5.77%, O 16.65%, P 16.11%, S 33.36%
Literature References: Cholinesterase inhibitor. Prepn: Willard, Henahan, US 2873228; US 3014058 (1959, 1961 both to FMC). Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969). Review of toxicology and human exposure: Toxicological Profile for Ethion (PB2000-108024, 2000) 218 pp.
Properties: Liquid, mp -13 to -12°. d420 1.220. nD20 1.5490. Vapor pressure: 1.5 ´ 10-6 mm Hg. Sol in xylene, methylated naphthalene, chloroform, acetone and kerosene + 1% methyl ethyl ketone or benzene; slightly sol in water. LD50 in female, male rats (mg/kg): 27, 65 orally; 62, 245 dermally (Gaines).
Melting point: mp -13 to -12°
Index of refraction: nD20 1.5490
Density: d420 1.220
Toxicity data: LD50 in female, male rats (mg/kg): 27, 65 orally; 62, 245 dermally (Gaines)
CAUTION: Potential symptoms of overexposure are eye, skin irritation; nausea, vomiting, abdominal cramps, diarrhea, salivation; headache, giddiness, vertigo, weakness; rhinorrhea, chest tightness; blurred vision, miosis; cardiac irregularities; muscle fasciculations; dyspnea. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 130.
Use: Insecticide; acaricide.
Therap-Cat-Vet: Ectoparasiticide.

Others monographs:
FenethazineAmmonium BromideBismuth AluminatePotassium Tetroxalate
Magnesium OleateEthanethiolThujic AcidEfavirenz
DiacetonamineIsobutyl CyanoacrylateSematilideEletriptan
Acetaldehyde Sodium BisulfitePhenylethanolamineTriazoxideMethoprene
©2016 DrugLead US FDA&EMEA