Etoxadrol
Title: Etoxadrol
CAS Registry Number: 28189-85-7
CAS Name: (2S)-2-[(2S,4S)]-2-(2-Ethyl-2-phenyl-1,3-dioxolan-4-yl)piperidine
Additional Names: (+)-2-(2-Ethyl-2-phenyl-1,3-dioxolan-4-yl)piperidine; 2-ethyl-2-phenyl-4-(2-piperidyl)-1,3-dioxolane
Molecular Formula: C16H23NO2
Molecular Weight: 261.36
Percent Composition: C 73.53%, H 8.87%, N 5.36%, O 12.24%
Literature References: Prepn of dl-form: Hardie et al., J. Med. Chem. 9, 127 (1966); Hardie, Halverstadt, US 3262938 (1966 to Cutter Labs). Resolution of the a-racemates: Allen et al., DE 2001616 (1970 to Cutter Labs), C.A. 74, 13129b (1971). Pharmacological studies: Traber et al., J. Pharmacol. Exp. Ther. 175, 395 (1970); Hidalgo et al., Anesth. Analg. 50, 231 (1971); Kelly et al., ibid. 262.
 
Derivative Type: (+)-Hydrochloride
CAS Registry Number: 23239-37-4
Manufacturers' Codes: CL-1848C
Trademarks: Thoxan (Cutter)
Molecular Formula: C16H23NO2.HCl
Molecular Weight: 297.82
Percent Composition: C 64.53%, H 8.12%, N 4.70%, O 10.74%, Cl 11.90%
Properties: Crystals from isopropanol, mp 221.5-222°. [a]D25 +16.63°.
Melting point: mp 221.5-222°
Optical Rotation: [a]D25 +16.63°
 
Therap-Cat: Anesthetic (intravenous).
Keywords: Anesthetic (Intravenous).

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