Flomoxef
Title: Flomoxef
CAS Registry Number: 99665-00-6
CAS Name: (6R-cis)-7-[[[(Difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Additional Names: 7-b-difluoromethylthioacetamido-7a-methoxy-3-[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thiomethyl]-1-oxa-3-cephem-4-carboxylic acid
Molecular Formula: C15H18F2N6O7S2
Molecular Weight: 496.47
Percent Composition: C 36.29%, H 3.65%, F 7.65%, N 16.93%, O 22.56%, S 12.92%
Literature References: Semi-synthetic oxacephalosporin antibiotic. Prepn: T. Tsuji et al., BE 898541; eidem, US 4532233 (1984, 1985 both to Shionogi); eidem, J. Antibiot. 38, 466 (1985). In vitro activity and b-lactamase stability: H. C. Neu, N.-X. Chin, Antimicrob. Agents Chemother. 30, 638 (1986).
Properties: Crystals from acetone + methylene chloride, mp 82.5-87.5°.
Melting point: mp 82.5-87.5°
 
Derivative Type: Sodium salt
CAS Registry Number: 92823-03-5
Manufacturers' Codes: 6315-S
Trademarks: Flumarin (Shionogi)
Molecular Formula: C15H17F2N6NaO7S2
Molecular Weight: 518.45
Percent Composition: C 34.75%, H 3.31%, F 7.33%, N 16.21%, Na 4.43%, O 21.60%, S 12.37%
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Oxacephems.

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