Fluprednisolone
Title: Fluprednisolone
CAS Registry Number: 53-34-9
CAS Name: (6a,11b)-6-Fluoro-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
Additional Names: 6a-fluoroprednisolone; 6a-fluoro-1,4-pregnadiene-11b,17a,21-triol-3,20-dione; 6a-fluoro-1-dehydrohydrocortisone
Manufacturers' Codes: U-7800; NSC-47439
Trademarks: Etadrol (Farmitalia)
Molecular Formula: C21H27FO5
Molecular Weight: 378.43
Percent Composition: C 66.65%, H 7.19%, F 5.02%, O 21.14%
Literature References: Prepn: Hogg, Spero, US 2841600 (1958 to Upjohn); Batres et al., DE 1079042 (1960 to Syntex); Lettré, Hotz, DE 1088953 (1960 to Bayer).
Properties: Crystals, mp 208-213°. [a]D +92°.
Melting point: mp 208-213°
Optical Rotation: [a]D +92°
 
Derivative Type: 21-Acetate
Molecular Formula: C23H29FO6
Molecular Weight: 420.47
Percent Composition: C 65.70%, H 6.95%, F 4.52%, O 22.83%
Properties: Crystals, mp 235-238°.
Melting point: mp 235-238°
 
Therap-Cat: Glucocorticoid; anti-inflammatory.
Therap-Cat-Vet: Anti-inflammatory.
Keywords: Glucocorticoid.

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